NAD+

NAD+ Buffer — Nicotinamide Adenine Dinucleotide

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells, serving as a critical electron carrier in metabolic redox reactions. As a central molecule in cellular energy production, DNA repair, and epigenetic regulation, NAD+ has become a focal point of longevity and mitochondrial research.

Biological Significance

NAD+ participates in over 500 enzymatic reactions and serves as a substrate for three major enzyme families: sirtuins (SIRT1-7), poly-ADP-ribose polymerases (PARPs), and cyclic ADP-ribose synthases (CD38/CD157). Sirtuin activation through NAD+ availability regulates mitochondrial biogenesis, oxidative stress defense, and inflammatory gene expression. Age-related NAD+ decline is associated with diminished mitochondrial function and altered cellular homeostasis.

Research Applications

• Mitochondrial function and biogenesis studies
• Sirtuin pathway activation and longevity research
• Cellular energy metabolism and ATP production
• DNA repair mechanism (PARP) investigations
• Age-related metabolic decline research
• Circadian rhythm and NAD+ oscillation studies

Product Specifications

• Purity: ≥99% (verified)
• Form: Buffered solution
• Storage: Store in cool, dry place; refrigerate after reconstitution
• Testing: USA lab tested, COA available

For research purposes only. Not for human use or consumption.